GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs4237643 | 1 | rs17596617 | chr11:43690717 | HSD17B12 | chr11:43702143-43878160:+ | -0.45 | -7.73 | 9.63E-14 | Forced vital capacity |
| BLCA | cis | rs12908161 | 1 | rs17600551 | chr15:85319258 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.17 | 3.85E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs17601029 | chr15:85347709 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.15 | 4.08E-5 | Schizophrenia |
| BLCA | cis | rs17608059 | 1 | rs17608059 | chr17:13910549 | CDRT15P | chr17:13927815-13928915:+ | -0.44 | -8.53 | 3.45E-16 | Temperament |
| BLCA | cis | rs2692194 | 1 | rs176084 | chr15:80014968 | MTHFS | chr15:80137320-80189370:- | -0.24 | -4.36 | 1.66E-5 | IgG glycosylation |
| BLCA | cis | rs6724465 | 1 | rs17608677 | chr2:219936871 | FAM134A | chr2:220042939-220050190:+ | 0.3 | 3.9 | 0.000112 | Height |
| BLCA | cis | rs6724465 | 1 | rs17608677 | chr2:219936871 | RNF25 | chr2:219528588-219536781:- | 0.25 | 3.99 | 7.9E-5 | Height |
| BLCA | cis | rs6724465 | 1 | rs17608677 | chr2:219936871 | ZNF142 | chr2:219502644-219524261:- | 0.29 | 4.02 | 7.13E-5 | Height |
| BLCA | cis | rs4776059 | 1 | rs17614559 | chr15:52878719 | ARPP19 | chr15:52839432-52861364:- | 0.23 | 4.24 | 2.78E-5 | Schizophrenia |
| BLCA | cis | rs11799420 | 1 | rs17649250 | chr1:171720586 | VAMP4 | chr1:171669298-171711214:- | 0.29 | 3.92 | 0.000106 | Hippocampal atrophy |
| BLCA | cis | rs80285556 | 1 | rs17661933 | chr19:50534520 | SIGLEC16 | chr19:50472912-50479075:+ | -0.53 | -5.27 | 2.3E-7 | antipsychotic drug dosage in schizophrenia or schizoaffective disorder |
| BLCA | cis | rs78153629 | 1 | rs17671194 | chr15:40667539 | C15orf23 | chr15:40674922-40686488:+ | 0.36 | 6.11 | 2.41E-9 | Heschl's gyrus morphology |
| BLCA | cis | rs78153629 | 1 | rs17671250 | chr15:40673124 | C15orf23 | chr15:40674922-40686488:+ | -0.25 | -4.44 | 1.18E-5 | Heschl's gyrus morphology |
| BLCA | cis | rs78153629 | 1 | rs17671250 | chr15:40673124 | IVD | chr15:40697686-40713512:+ | 0.33 | 4.55 | 7.34E-6 | Heschl's gyrus morphology |
| BLCA | cis | rs9475752 | 1 | rs17685143 | chr6:56774788 | BEND6 | chr6:56819773-56892138:+ | -0.31 | -4.28 | 2.36E-5 | Menarche (age at onset) |